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In enzymology, an acyl-() desaturase () is an enzyme that catalyzes the chemical reaction :stearoyl-() + reduced acceptor + O2 oleoyl-() + acceptor + 2 H2O The systematic name of this enzyme class is acyl-(), hydrogen-donor:oxygen oxidoreductase. Other names in common use include stearyl acyl carrier protein desaturase, and stearyl-ACP desaturase. This enzyme participates in polyunsaturated fatty acid biosynthesis. It employs one cofactor, ferredoxin. ==Reaction== The 3 substrates of this enzyme are stearoyl-(acyl-carrier-protein), reduced acceptor, and O2, whereas its 3 products are oleoyl-(acyl-carrier-protein), acceptor, and H2O. The precise mechanism of this class of enzymes is not known, however recent studies using the kinetic isotope effect suggest that the rate limiting step is the removal of a hydrogen from the carbon nearest the carboxylic acid group. The diiron cluster moves through to a peroxo intermediate which can then dehydrate the short-lived alcohol intermediate, liberating water. There are a variety of specific enzymes within this class that attack using this mechanism, but do so at different points along the carbon chain of their respective fatty acids 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Acyl-(acyl-carrier-protein) desaturase」の詳細全文を読む スポンサード リンク
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